High-dose dexamethasone in low pain responders undergoing total knee arthroplasty: a randomised double-blind trial

Postoperative pain after total knee arthroplasty (TKA) is a continuing problem despite optimised multimodal analgesia. Previous studies have shown preoperative glucocorticoids to reduce postoperative pain, but knowledge about specific doses and effects in specific patient groups is lacking. A two-ce...

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Veröffentlicht in:	British journal of anaesthesia : BJA 2023-03, Vol.130 (3), p.322-330
Hauptverfasser:	Nielsen, Niklas I., Kehlet, Henrik, Gromov, Kirill, Troelsen, Anders, Husted, Henrik, Varnum, Claus, Kjærsgaard-Andersen, Per, Rasmussen, Lasse E., Pleckaitiene, Lina, Foss, Nicolai B.
Format:	Artikel
Sprache:	eng
Schlagworte:	anaesthesia Analgesics, Opioid Anesthetics, Local Antiemetics - therapeutic use Arthroplasty, Replacement, Knee - adverse effects C-Reactive Protein dexamethasone Dexamethasone - therapeutic use Double-Blind Method fast-track surgery Humans multimodal analgesia Pain, Postoperative - diagnosis Pain, Postoperative - drug therapy Pain, Postoperative - prevention & control perioperative medicine postoperative pain total knee arthroplasty
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