Synthesis of CF3‑Substituted Alkylamines, 1,2-Bisazoles, and 1,4,5,6-Tetrahydro-1,2,4-triazines from Newly Designed Tetrazole-Activated Trifluoromethyl Alkenes

A new class of Michael acceptor, tetrazolyl-trifluoromethyl alkenes, has been discovered. They readily undergo Michael-type addition instead of addition–elimination reaction with aliphatic amines and azoles to furnish β-trifluoromethyl alkylamines and CF3-substituted 1,2-bisazole derivatives, respec...

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Veröffentlicht in:	Organic letters 2022-12, Vol.24 (50), p.9301-9305
Hauptverfasser:	Chen, Shu-Jie, He, Zhi-Qing, Chen, Guo-Shu, Zhao, Cheng, Chen, Chang-Ping, Zhuang, Yin-Yin, Chen, Long, Liu, Yun-Lin
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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