Medullary carcinoma of the ampulla has distinct clinicopathologic characteristics including common association with microsatellite instability and PD-L1 expression

Medullary carcinomas have not yet been fully characterized in the ampulla. Here, 359 ampullary carcinomas (ACs) were reviewed and 11 medullary-type carcinomas (3%) were found and analyzed. In addition to the diagnostic medullary pattern, 6 showed focal mucinous and 8 had focal abortive gland-like fo...

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Veröffentlicht in:	Human pathology 2023-01, Vol.131, p.38-46
Hauptverfasser:	Xue, Yue, Balci, Serdar, Pehlivanoglu, Burcin, Muraki, Takashi, Memis, Bahar, Saka, Burcu, Kim, Grace, Bandyopadhyay, Sudeshna, Knight, Jessica, El-Rayes, Bassel, Kooby, David, Maithel, Shishir K., Sarmiento, Juan, Basturk, Olca, Reid, Michelle D., Adsay, Volkan
Format:	Artikel
Sprache:	eng
Schlagworte:	Ampullary carcinoma B7-H1 Antigen - analysis Biomarkers, Tumor - analysis Carcinoma, Medullary - genetics Carcinoma, Neuroendocrine Common Bile Duct Neoplasms - genetics Common Bile Duct Neoplasms - pathology DNA Mismatch Repair DNA mismatch repair protein Duodenal Neoplasms Humans Medullary carcinoma Microsatellite Instability Pancreatic Neoplasms Programmed cell death ligand-1
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