Polygenic risk scores for the prediction of cardiometabolic disease

Cardiometabolic diseases contribute more to global morbidity and mortality than any other group of disorders. Polygenic risk scores (PRSs), the weighted summation of individually small-effect genetic variants, represent an advance in our ability to predict the development and complications of cardio...

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Veröffentlicht in:	European heart journal 2023-01, Vol.44 (2), p.89-99
Hauptverfasser:	O'Sullivan, Jack W, Ashley, Euan A, Elliott, Perry M
Format:	Artikel
Sprache:	eng
Schlagworte:	Atrial Fibrillation Brain Ischemia Coronary Artery Disease - epidemiology Coronary Artery Disease - genetics Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - genetics Genetic Predisposition to Disease - genetics Genome-Wide Association Study Humans Hypertension - epidemiology Hypertension - genetics Risk Factors Stroke
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