Free Fatty Acids from Type 2 Diabetes Mellitus Serum Remodel Mesenchymal Stem Cell Lipids, Hindering Differentiation into Primordial Germ Cells

Type 2 diabetes mellitus (T2DM) adversely affects the essential characteristics of adipose tissue-derived mesenchymal stem cells (AdMSCs). Given that T2DM is associated with an altered serum free fatty acid (FFA) profile, we examined whether diabetic serum FFAs influence the viability, differentiati...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Applied biochemistry and biotechnology 2023-05, Vol.195 (5), p.3011-3026
Hauptverfasser:	Norouzi, Zahra, Zarezadeh, Reza, Mehdizadeh, Amir, Niafar, Mitra, Germeyer, Ariane, Fayyazpour, Parisa, Fayezi, Shabnam
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Biochemistry Biomarkers Biotechnology Cell Differentiation Cell viability Chemistry Chemistry and Materials Science Chromatography Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - metabolism Differentiation (biology) Fatty acid composition Fatty acids Fatty Acids - metabolism Fatty Acids, Nonesterified - metabolism Female Fractionation Gene expression Germ cells Germ Cells - metabolism Humans Linoleic acid Linoleic Acids Lipids Liquid chromatography Mesenchymal Stem Cells Original Article Phospholipids Stem cells Thin layer chromatography Triglycerides
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!