Temporal molecular program of human hematopoietic stem and progenitor cells after birth

Hematopoietic stem and progenitor cells (HSPCs) give rise to the blood system and maintain hematopoiesis throughout the human lifespan. Here, we report a transcriptional census of human bone-marrow-derived HSPCs from the neonate, infant, child, adult, and aging stages, showing two subpopulations of...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Developmental cell 2022-12, Vol.57 (24), p.2745-2760.e6
Hauptverfasser:	Zhang, Yawen, Xie, Xiaowei, Huang, Yaojing, Liu, Mengyao, Li, Qiaochuan, Luo, Jianming, He, Yunyan, Yin, Xiuxiu, Ma, Shihui, Cao, Wenbin, Chen, Shulian, Peng, Jun, Guo, Jiaojiao, Zhou, Wen, Luo, Hongbo, Dong, Fang, Cheng, Hui, Hao, Sha, Hu, Linping, Zhu, Ping, Cheng, Tao
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Cell Differentiation Child Hematopoiesis hematopoietic stem and progenitor cells Hematopoietic Stem Cells - metabolism human hematopoiesis Humans Infant Infant, Newborn post-natal development single-cell RNA-seq
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!