Synaptic activity-dependent changes in the hippocampal palmitoylome

Dynamic protein S-palmitoylation is critical for neuronal function, development, and synaptic plasticity. Synaptic activity-dependent changes in palmitoylation have been reported for a small number of proteins. Here, we characterized the palmitoylome in the hippocampi of male mice before and after c...

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Veröffentlicht in:	Science signaling 2022-12, Vol.15 (763), p.eadd2519-eadd2519
Hauptverfasser:	Nasseri, Glory G, Matin, Nusrat, Wild, Angela R, Tosefsky, Kira, Flibotte, Stephane, Stacey, R Greg, Hollman, Rocio B, Foster, Leonard J, Bamji, Shernaz X
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cognition Fear conditioning Hippocampus Learning Lipids Localization Male Metabolism Mice Palmitoylation Plasticity Protein transport Proteins Proteomics Rats Spine Synaptic plasticity Synaptic strength α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors
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