Development of a quaternary ammonium photoswitchable antagonist of NMDA receptors

NMDA receptors play critical roles in numerous physiological and pathological processes in CNS that requires development of modulating ligands. In particular, photoswitchable compounds that selectively target NMDA receptors would be particularly useful for analysis of receptor contributions to vario...

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Veröffentlicht in:	European journal of pharmacology 2023-01, Vol.938, p.175448-175448, Article 175448
Hauptverfasser:	Nikolaev, Maxim V., Strashkov, Daniil M., Ryazantsev, Mikhail N., Tikhonov, Denis B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Ammonium Compounds - pharmacology Animals Azo Compounds - chemistry Azo Compounds - pharmacology Inhibition NMDA receptor Photopharmacology Photoswitches Rats Receptors, Glutamate Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors
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