Particulate matter 2.5 induces the skin barrier dysfunction and cutaneous inflammation via AhR‐ and T helper 17 cell‐related genes in human skin tissue as identified via transcriptome analysis

Particulate matter (PM2.5) is an environmental pollutant causing skin inflammatory diseases via epidermal barrier damage. However, the mechanism and related gene expression induced by PM2.5 remains unclear. Our aim was to determine the effect of PM2.5 on human skin tissue ex vivo, and elucidate the...

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Veröffentlicht in:	Experimental dermatology 2023-04, Vol.32 (4), p.547-554
Hauptverfasser:	Kim, Han Bi, Choi, Min Gyu, Chung, Bo Young, Um, Ji Young, Kim, Jin Cheol, Park, Chun Wook, Kim, Hye One
Format:	Artikel
Sprache:	eng
Schlagworte:	aryl hydrocarbon receptor (AhR) Cell lines Cornified Envelope Proline-Rich Proteins - genetics Cytochrome P450 epidermal barrier Gene expression Gene Expression Profiling Genes Helper cells Humans Inflammation - genetics Inflammation - metabolism Inflammatory diseases Interleukin 6 Lymphocytes T Particulate matter Particulate Matter - toxicity particulate matter 2.5 (PM2.5) Proteins Receptors, Aryl Hydrocarbon - genetics Receptors, Aryl Hydrocarbon - metabolism Skin - immunology Skin diseases Th17 cell Th17 Cells - metabolism transcriptome analysis Transcriptomes
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