DOK7 Promotes NMJ Regeneration After Nerve Injury

Motor function recovery from injury requires the regeneration of not only muscle fibers, but also the neuromuscular junction—the synapse between motor nerve terminals and muscle fibers. However, unlike muscle regeneration which has been extensively studied, little is known about the molecular mechan...

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Veröffentlicht in:	Molecular neurobiology 2023-03, Vol.60 (3), p.1453-1464
Hauptverfasser:	Kosco, Ethan D., Jing, Hongyang, Chen, Peng, Xiong, Wen-Cheng, Samuels, Ivy S., Mei, Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	Agrin Agrin - metabolism Animals Antibodies Biomedical and Life Sciences Biomedicine Cell Biology Hypotheses Injuries Mice Molecular modelling Muscle Proteins - metabolism Muscles Nerve endings Neurobiology Neurology Neuromuscular Junction - injuries Neuromuscular Junction - physiology Neuromuscular junctions Neurosciences Proteins Receptor density Receptors, Cholinergic - metabolism Recovery of function Regeneration Reinnervation Synapses Synapses - metabolism
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