CaMK phosphatase (CaMKP/POPX2/PPM1F) inhibitors suppress the migration of human breast cancer MDA-MB-231 cells with loss of polarized morphology

CaMK phosphatase (CaMKP/POPX2/PPM1F) is a Ser/Thr protein phosphatase that belongs to the PPM family. Accumulating evidence suggests that CaMKP is involved in the pathogenesis of various diseases, including cancer. To clarify the relationship between CaMKP activity and human breast cancer cell motil...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemical and biophysical research communications 2023-01, Vol.639, p.1-8
Hauptverfasser:	Akizuki, Kazutoshi, Shimoda, Nao, Ozaki, Hana, Yamazaki, Takeshi, Hirano, Tetsuo, Ishihara, Yasuhiro, Sueyoshi, Noriyuki, Kameshita, Isamu, Murai, Toshiyuki, Ishida, Atsuhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast Neoplasms calcium-calmodulin-dependent protein kinase Calcium-Calmodulin-Dependent Protein Kinases Cell Line, Tumor Cell migration Cell Movement cytotoxicity Dephosphorylation family Female Humans Low cytotoxicity MDA-MB-231 Cells metastasis Naphthols neoplasm cells Phosphatase assay Phosphoprotein Phosphatases - metabolism phosphorylation Specific inhibitor therapeutics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!