Advantages of the retroperitoneal retrocolic space as the transplant site for encapsulated xenogeneic islets

Objective Islet allotransplantation has demonstrated improved clinical outcomes using the hepatic portal vein as the standard infusion method. However, the current implantation site is not ideal due to the short‐term thrombotic and long‐term immune destruction. Meanwhile, the shortage of human organ...

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Veröffentlicht in:	Xenotransplantation (Københaven) 2023-01, Vol.30 (1), p.e12787-n/a
Hauptverfasser:	Geng, Zhen, Zhang, Qi, Li, Ting, Huang, Ting, Wang, Hailian, Zhou, Qiao, Deng, Shaoping, Zhao, Yanshuang, Li, Yanjiao, Cheng, Chunming, Gonelle‐Gispert, Carmen, Buhler, Leo H., Wang, Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	alginate (Alg) Alginic acid Allografts Animals Diabetes mellitus (insulin dependent) Diabetes Mellitus, Experimental - surgery Encapsulation Glucagon Humans Hydrogels Insulin Islet cells Islet xenotransplantation Islets of Langerhans - surgery Islets of Langerhans Transplantation - methods Kidneys Mice Neonates Organ donors Pancreatic islet transplantation Peritoneum poly‐ethylene‐imine (PEI) Portal vein Rats Retroperitoneal Space Swine Transplantation, Heterologous - methods Transplants & implants Xenografts
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