Genetically encoded dual fluorophore reporters for graded oxygen-sensing in light microscopy

Hypoxia is an essential regulator of cell metabolism, affects cell migration and angiogenesis during development and contributes to a wide range of pathological conditions. Multiple techniques to assess hypoxia through oxygen-imaging have been developed. However, significant limitations include low...

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Veröffentlicht in:	Biosensors & bioelectronics 2023-02, Vol.221, p.114917-114917, Article 114917
Hauptverfasser:	Bauer, Nadine, Maisuls, Ivan, Pereira da Graça, Abel, Reinhardt, Dirk, Erapaneedi, Raghu, Kirschnick, Nils, Schäfers, Michael, Grashoff, Carsten, Landfester, Katharina, Vestweber, Dietmar, Strassert, Cristian A., Kiefer, Friedemann
Format:	Artikel
Sprache:	eng
Schlagworte:	Fluorescent reporter FRET-FLIM Live-cell imaging Oxygen-sensing Ratiometric sensor Tumor-hypoxia
Online-Zugang:	Volltext
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