RBM24 controls cardiac QT interval through CaMKIIδ splicing

Calcium/calmodulin-dependent kinase II delta ( CaMKIIδ ) is the predominant cardiac isoform and it is alternatively spliced to generate multiple variants. Variable variants allow for distinct localization and potentially different functions in the heart. Dysregulation of CaMKIIδ splicing has been de...

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Veröffentlicht in:	Cellular and molecular life sciences : CMLS 2022-12, Vol.79 (12), p.613-613, Article 613
Hauptverfasser:	Liu, Jing, Wang, Ke, Liu, Xingyang, Pan, Lei, Zhou, Wanlu, Huang, Jingru, Liu, Hongli, Su, Zhiying, Xu, Xiu Qin
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Abnormalities Action potential Action Potentials - genetics Alternative splicing Animals Arrhythmia Biochemistry Biomedical and Life Sciences Biomedicine Calcium ions Calcium-binding protein Calmodulin Cardiomyocytes Cardiovascular diseases Cell Biology Coronary artery disease Heart Diseases Heart Ventricles Humans Hypertrophy Kinases Life Sciences Localization Mice Mice, Knockout Myocytes, Cardiac Original Article Pathogenesis Prolongation RNA Splicing - genetics RNA-Binding Proteins - genetics Splicing Stem cells Ventricle
Online-Zugang:	Volltext
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