Impaired Efferocytosis by Synovial Macrophages in Patients With Knee Osteoarthritis

Objective Osteoarthritis (OA) exposes all joint tissues to physiologic stresses, increasing the need to clear apoptotic cells from tissues, including the synovium. We undertook this study to assess the burden of apoptotic cells in synovial tissue in patients with late‐stage knee OA and to investigat...

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Veröffentlicht in:	Arthritis & rheumatology (Hoboken, N.J.) N.J.), 2023-05, Vol.75 (5), p.685-696
Hauptverfasser:	Del Sordo, Luigi, Blackler, Garth B., Philpott, Holly T., Riviere, Jared, Gunaratnam, Lakshman, Heit, Bryan, Appleton, C. Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Arthritis Arthroplasty (knee) Blood Caspase-3 CD14 antigen Humans Immunofluorescence Inflammation Knee Macrophages Osteoarthritis Osteoarthritis, Knee - surgery Pain Peripheral blood Synovial Fluid Synovial Membrane Synovium Tissues
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