TBBPA induces inflammation, apoptosis, and necrosis of skeletal muscle in mice through the ROS/Nrf2/TNF-α signaling pathway

Tetrabromobisphenol A (TBBPA) is present in large quantities in the environment due to its widespread use. And TBBPA is capable of accumulating in animals, entering the ecological chain and causing widespread damage to organisms. TBBPA is capable of causing the onset of oxidative stress, which induc...

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Veröffentlicht in:	Environmental pollution (1987) 2023-01, Vol.317, p.120745-120745, Article 120745
Hauptverfasser:	Zhang, Qirui, Wang, Shengchen, Wang, Fuhan, Guo, Mengyao, Xu, Shiwen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Cell damage dose response Inflammation Inflammation - chemically induced Inflammation - metabolism malondialdehyde Mice Muscle, Skeletal myoblasts necrosis Necrosis - metabolism NF-E2-Related Factor 2 - metabolism Nrf2 Oxidative stress Oxidative Stress - physiology pollution reactive oxygen species Reactive Oxygen Species - metabolism Signal Transduction skeletal muscle TBBPA Tumor Necrosis Factor-alpha - metabolism
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