Inhibition of ferroptosis of renal tubular cells with total flavones of Abelmoschus manihot alleviates diabetic tubulopathy

Ferroptosis-related renal tubular lesions play important roles in diabetic kidney disease (DKD) progression, and these pathophysiological responses are collectively described as diabetic tubulopathy (DT), which lacks an effective treatment. Total flavones from Abelmoschus manihot (TFA), a natural ex...

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Veröffentlicht in:	Anatomical record (Hoboken, N.J. : 2007) N.J. : 2007), 2023-12, Vol.306 (12), p.3199-3213
Hauptverfasser:	Wang, Mei-Zi, Cai, Yu-Feng, Fang, Qi-Jun, Liu, Ying-Lu, Wang, Jie, Chen, Jia-Xin, Fu, Yan, Wan, Bing-Ying, Tu, Yue, Wu, Wei, Wan, Yi-Gang, Mu, Geng-Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	Abelmoschus Abelmoschus manihot Advanced glycosylation end products Animals Diabetes Diabetes mellitus Diabetes Mellitus - drug therapy Diabetic Nephropathies - drug therapy Diabetic Nephropathies - metabolism Ferroptosis Flavones Flavones - pharmacology Flavones - therapeutic use Glycosylation Humans Iron - therapeutic use Kidney diseases Lipid peroxidation Rats
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