Macrophage immunotherapy: overcoming impediments to realize promise

The overuse and misuse of the macrophage ‘M1–M2 paradigm’ and the terms ‘inflammatory’ and ‘anti-inflammatory’ belie accurate description of macrophages and have hindered experimental design.The precise description of derived and isolated macrophages, including source, growth factors, stimuli, and c...

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Veröffentlicht in:	Trends in immunology 2022-12, Vol.43 (12), p.959-968
Hauptverfasser:	Sly, Laura M., McKay, Derek M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone marrow CAR macrophage Cell therapy cellular immunotherapy Cytokines Disease Gene expression Homeostasis Humans Immunologic Factors Immunotherapy Leukocyte Count M1-M2 paradigm Macrophages Mammals Nitric oxide Pathophysiology Precision Medicine Subpopulations
Online-Zugang:	Volltext
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