Features of the Effects of Glutamatergic System Modulators in the Model of Hyperthermal Seizures in Rat Pups

We studied the effect of lamotrigine, an anticonvulsant inhibiting the presynaptic release of glutamate, and LY341495, an antagonist of metabotropic glutamate 2/3 receptors, on the development of hyperthermic seizures and the content of LPO products in the brain of 8-10-day-old Wistar rats. Rat pups...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2022-11, Vol.174 (1), p.43-46
Hauptverfasser:	Bashkatova, V. G., Bogdanova, N. G., Nazarova, G. A., Sudakov, S. K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Anticonvulsants Biomedical and Life Sciences Biomedicine Brain research Cell Biology Cerebral cortex Convulsions & seizures Drug dosages Fever Glutamate Glutamatergic transmission Glutamic acid receptors (metabotropic) Hyperthermia Internal Medicine Juveniles Laboratory animals Laboratory Medicine Lamotrigine Latency Medical research Oxidative stress Pathology Physiology Seizures Seizures (Medicine) Toxicology
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