Higher Complication Rates for Total versus Partial Thyroidectomy in the Pediatric Population
This study aims to analyze the relative risks for total thyroidectomies by comparing complication rates for total versus partial thyroidectomy in the pediatric population. We queried the Kids’ Inpatient Database (KID) 1997-2012 for all cases of total (n = 3253) or partial (n = 2380) thyroidectomy. W...
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Veröffentlicht in: | The Journal of surgical research 2023-03, Vol.283, p.449-458 |
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creator | Willobee, Brent A. Huerta, Carlos T. Quiroz, Hallie J. Mao, Melissa L. Ryon, Emily L. Ferrantella, Anthony Thorson, Chad M. Sola, Juan E. Perez, Eduardo A. |
description | This study aims to analyze the relative risks for total thyroidectomies by comparing complication rates for total versus partial thyroidectomy in the pediatric population.
We queried the Kids’ Inpatient Database (KID) 1997-2012 for all cases of total (n = 3253) or partial (n = 2380) thyroidectomy. We then designed a propensity score matching model and compared total versus partial thyroidectomy based on surgical complications and outcomes.
In our cohort, the median age was 16 years and 79% were females. Those treated at a specialty pediatric hospital or pediatric unit in a general hospital comprised 73% of all patients. The most common indications for surgery were malignancy (46%) and goiter (42%). The most common complications were hypocalcemia and nerve injury with an unweighted incidence of 9% (n = 174) and 3% (n = 57) respectively. When compared to partial thyroidectomy, total thyroidectomy was associated with increased rates of postoperative complications. Additionally, the median length of stay was significantly higher for total thyroidectomy patients.
This is the largest analysis to date comparing outcomes for total versus partial thyroidectomy in the pediatric population. Surgeons should consider the increased rates of hypocalcemia and nerve injury complications when selecting total compared to partial thyroidectomy in children. |
doi_str_mv | 10.1016/j.jss.2022.10.074 |
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We queried the Kids’ Inpatient Database (KID) 1997-2012 for all cases of total (n = 3253) or partial (n = 2380) thyroidectomy. We then designed a propensity score matching model and compared total versus partial thyroidectomy based on surgical complications and outcomes.
In our cohort, the median age was 16 years and 79% were females. Those treated at a specialty pediatric hospital or pediatric unit in a general hospital comprised 73% of all patients. The most common indications for surgery were malignancy (46%) and goiter (42%). The most common complications were hypocalcemia and nerve injury with an unweighted incidence of 9% (n = 174) and 3% (n = 57) respectively. When compared to partial thyroidectomy, total thyroidectomy was associated with increased rates of postoperative complications. Additionally, the median length of stay was significantly higher for total thyroidectomy patients.
This is the largest analysis to date comparing outcomes for total versus partial thyroidectomy in the pediatric population. Surgeons should consider the increased rates of hypocalcemia and nerve injury complications when selecting total compared to partial thyroidectomy in children.</description><identifier>ISSN: 0022-4804</identifier><identifier>EISSN: 1095-8673</identifier><identifier>DOI: 10.1016/j.jss.2022.10.074</identifier><identifier>PMID: 36434841</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adolescent ; Child ; Female ; Humans ; Hypocalcemia - epidemiology ; Inpatients ; Kids' inpatient database ; Male ; Outcomes ; Partial thyroidectomy ; Pediatric thyroidectomy ; Postoperative Complications - etiology ; Retrospective Studies ; Surgeons ; Thyroid disease ; Thyroidectomy - adverse effects ; Total thyroidectomy</subject><ispartof>The Journal of surgical research, 2023-03, Vol.283, p.449-458</ispartof><rights>2022 Elsevier Inc.</rights><rights>Copyright © 2022 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c353t-15703ca18aa15ca73a70f99f71a693fa7d3950dd35757293391808e77044dffb3</citedby><cites>FETCH-LOGICAL-c353t-15703ca18aa15ca73a70f99f71a693fa7d3950dd35757293391808e77044dffb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0022480422007090$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65534</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36434841$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Willobee, Brent A.</creatorcontrib><creatorcontrib>Huerta, Carlos T.</creatorcontrib><creatorcontrib>Quiroz, Hallie J.</creatorcontrib><creatorcontrib>Mao, Melissa L.</creatorcontrib><creatorcontrib>Ryon, Emily L.</creatorcontrib><creatorcontrib>Ferrantella, Anthony</creatorcontrib><creatorcontrib>Thorson, Chad M.</creatorcontrib><creatorcontrib>Sola, Juan E.</creatorcontrib><creatorcontrib>Perez, Eduardo A.</creatorcontrib><title>Higher Complication Rates for Total versus Partial Thyroidectomy in the Pediatric Population</title><title>The Journal of surgical research</title><addtitle>J Surg Res</addtitle><description>This study aims to analyze the relative risks for total thyroidectomies by comparing complication rates for total versus partial thyroidectomy in the pediatric population.
We queried the Kids’ Inpatient Database (KID) 1997-2012 for all cases of total (n = 3253) or partial (n = 2380) thyroidectomy. We then designed a propensity score matching model and compared total versus partial thyroidectomy based on surgical complications and outcomes.
In our cohort, the median age was 16 years and 79% were females. Those treated at a specialty pediatric hospital or pediatric unit in a general hospital comprised 73% of all patients. The most common indications for surgery were malignancy (46%) and goiter (42%). The most common complications were hypocalcemia and nerve injury with an unweighted incidence of 9% (n = 174) and 3% (n = 57) respectively. When compared to partial thyroidectomy, total thyroidectomy was associated with increased rates of postoperative complications. Additionally, the median length of stay was significantly higher for total thyroidectomy patients.
This is the largest analysis to date comparing outcomes for total versus partial thyroidectomy in the pediatric population. Surgeons should consider the increased rates of hypocalcemia and nerve injury complications when selecting total compared to partial thyroidectomy in children.</description><subject>Adolescent</subject><subject>Child</subject><subject>Female</subject><subject>Humans</subject><subject>Hypocalcemia - epidemiology</subject><subject>Inpatients</subject><subject>Kids' inpatient database</subject><subject>Male</subject><subject>Outcomes</subject><subject>Partial thyroidectomy</subject><subject>Pediatric thyroidectomy</subject><subject>Postoperative Complications - etiology</subject><subject>Retrospective Studies</subject><subject>Surgeons</subject><subject>Thyroid disease</subject><subject>Thyroidectomy - adverse effects</subject><subject>Total thyroidectomy</subject><issn>0022-4804</issn><issn>1095-8673</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kFFLwzAUhYMobk5_gC-SR19akyZtWnySoU4YOGS-CSFLUpfSNjNJB_v3Zm766NPl3HvOgfsBcI1RihEu7pq08T7NUJZFnSJGT8AYoypPyoKRUzBG8ZLQEtERuPC-QVFXjJyDESkooSXFY_AxM59r7eDUdpvWSBGM7eGbCNrD2jq4tEG0cKudHzxcCBdMlMv1zlmjtAy220HTw7DWcKGVEcEZCRd2M7Q_RZfgrBat11fHOQHvT4_L6SyZvz6_TB_miSQ5CQnOGSJS4FIInEvBiGCorqqaYVFUpBZMkSpHSpGc5SyrCKlwiUrNGKJU1fWKTMDtoXfj7NegfeCd8VK3rei1HTzPGEU5Rhkj0YoPVums907XfONMJ9yOY8T3UHnDI1S-h7pfRagxc3OsH1adVn-JX4rRcH8w6Pjk1mjHvTS6lxGJi5S4suaf-m_FFoeL</recordid><startdate>202303</startdate><enddate>202303</enddate><creator>Willobee, Brent A.</creator><creator>Huerta, Carlos T.</creator><creator>Quiroz, Hallie J.</creator><creator>Mao, Melissa L.</creator><creator>Ryon, Emily L.</creator><creator>Ferrantella, Anthony</creator><creator>Thorson, Chad M.</creator><creator>Sola, Juan E.</creator><creator>Perez, Eduardo A.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>202303</creationdate><title>Higher Complication Rates for Total versus Partial Thyroidectomy in the Pediatric Population</title><author>Willobee, Brent A. ; Huerta, Carlos T. ; Quiroz, Hallie J. ; Mao, Melissa L. ; Ryon, Emily L. ; Ferrantella, Anthony ; Thorson, Chad M. ; Sola, Juan E. ; Perez, Eduardo A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c353t-15703ca18aa15ca73a70f99f71a693fa7d3950dd35757293391808e77044dffb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Adolescent</topic><topic>Child</topic><topic>Female</topic><topic>Humans</topic><topic>Hypocalcemia - epidemiology</topic><topic>Inpatients</topic><topic>Kids' inpatient database</topic><topic>Male</topic><topic>Outcomes</topic><topic>Partial thyroidectomy</topic><topic>Pediatric thyroidectomy</topic><topic>Postoperative Complications - etiology</topic><topic>Retrospective Studies</topic><topic>Surgeons</topic><topic>Thyroid disease</topic><topic>Thyroidectomy - adverse effects</topic><topic>Total thyroidectomy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Willobee, Brent A.</creatorcontrib><creatorcontrib>Huerta, Carlos T.</creatorcontrib><creatorcontrib>Quiroz, Hallie J.</creatorcontrib><creatorcontrib>Mao, Melissa L.</creatorcontrib><creatorcontrib>Ryon, Emily L.</creatorcontrib><creatorcontrib>Ferrantella, Anthony</creatorcontrib><creatorcontrib>Thorson, Chad M.</creatorcontrib><creatorcontrib>Sola, Juan E.</creatorcontrib><creatorcontrib>Perez, Eduardo A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of surgical research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Willobee, Brent A.</au><au>Huerta, Carlos T.</au><au>Quiroz, Hallie J.</au><au>Mao, Melissa L.</au><au>Ryon, Emily L.</au><au>Ferrantella, Anthony</au><au>Thorson, Chad M.</au><au>Sola, Juan E.</au><au>Perez, Eduardo A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Higher Complication Rates for Total versus Partial Thyroidectomy in the Pediatric Population</atitle><jtitle>The Journal of surgical research</jtitle><addtitle>J Surg Res</addtitle><date>2023-03</date><risdate>2023</risdate><volume>283</volume><spage>449</spage><epage>458</epage><pages>449-458</pages><issn>0022-4804</issn><eissn>1095-8673</eissn><abstract>This study aims to analyze the relative risks for total thyroidectomies by comparing complication rates for total versus partial thyroidectomy in the pediatric population.
We queried the Kids’ Inpatient Database (KID) 1997-2012 for all cases of total (n = 3253) or partial (n = 2380) thyroidectomy. We then designed a propensity score matching model and compared total versus partial thyroidectomy based on surgical complications and outcomes.
In our cohort, the median age was 16 years and 79% were females. Those treated at a specialty pediatric hospital or pediatric unit in a general hospital comprised 73% of all patients. The most common indications for surgery were malignancy (46%) and goiter (42%). The most common complications were hypocalcemia and nerve injury with an unweighted incidence of 9% (n = 174) and 3% (n = 57) respectively. When compared to partial thyroidectomy, total thyroidectomy was associated with increased rates of postoperative complications. Additionally, the median length of stay was significantly higher for total thyroidectomy patients.
This is the largest analysis to date comparing outcomes for total versus partial thyroidectomy in the pediatric population. Surgeons should consider the increased rates of hypocalcemia and nerve injury complications when selecting total compared to partial thyroidectomy in children.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>36434841</pmid><doi>10.1016/j.jss.2022.10.074</doi><tpages>10</tpages></addata></record> |
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subjects | Adolescent Child Female Humans Hypocalcemia - epidemiology Inpatients Kids' inpatient database Male Outcomes Partial thyroidectomy Pediatric thyroidectomy Postoperative Complications - etiology Retrospective Studies Surgeons Thyroid disease Thyroidectomy - adverse effects Total thyroidectomy |
title | Higher Complication Rates for Total versus Partial Thyroidectomy in the Pediatric Population |
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