The comparison of prognoses between total and distal gastrectomy for gastric cancer in elderly patients ≥ 80 years old
Purpose In Japan, the number of distal gastrectomy for patients ≥ 80 years old is increasing, whereas that of total gastrectomy is decreasing. Surgeons seem to avoid total gastrectomy for elderly patients. Total gastrectomy is reported to have a poorer prognosis than distal gastrectomy, and postoper...
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| Veröffentlicht in: | Surgery today (Tokyo, Japan) Japan), 2023-05, Vol.53 (5), p.569-577 |
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| container_title | Surgery today (Tokyo, Japan) |
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| creator | Endo, Shunji Yamatsuji, Tomoki Fujiwara, Yoshinori Higashida, Masaharu Kubota, Hisako Tanaka, Hironori Ito, Yoshitomo Okada, Toshimasa Yoshiatsu, Kazuhiko Ueno, Tomio |
| description | Purpose
In Japan, the number of distal gastrectomy for patients ≥ 80 years old is increasing, whereas that of total gastrectomy is decreasing. Surgeons seem to avoid total gastrectomy for elderly patients. Total gastrectomy is reported to have a poorer prognosis than distal gastrectomy, and postoperative pneumonia may be involved in the cause.
Methods
The medical records of 39 and 108 patients ≥ 80 years old who underwent total and distal gastrectomy, respectively, at 2 affiliated institutions between 2010 and 2019 were retrospectively reviewed. Prognoses were compared between the two groups, focusing on death from pneumonia.
Results
The median overall survival time after total and distal gastrectomy was 21.3 and 74.1 months, respectively, with a significantly poorer prognosis after total gastrectomy than after distal gastrectomy (
p
|
| doi_str_mv | 10.1007/s00595-022-02599-0 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2739744002</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2739744002</sourcerecordid><originalsourceid>FETCH-LOGICAL-c371t-296878d6e6cba0143b6c3e00e6e9058b917863a63896b7cdf6569e5d4d04761b3</originalsourceid><addsrcrecordid>eNp9kD1uFTEUhS1ERB4JG6BALmkmXI9n_FOiiJ9IkWiS2vLYdx4TzdgP20_oFUhpswsaNsJSspI4TKCkuL62fM6RzkfIawZnDEC-ywC97hto2zq91g08IxvWcdG0ivHnZAO6Yw1rNTsmL3O-AWg7BfCCHHPRMdXLfkN-XH1F6uKys2nKMdA40l2K2xAzZjpg-Y4YaInFztQGT_2UH69bm0tCV-JyoGNM63ty1NngMNEpUJw9pvlAd7ZMGEq-v727v_tVTwW_fx7Qpkzj7E_J0WjnjK-e9gm5_vjh6vxzc_nl08X5-8vGcclK02qhpPIChRss1IaDcBwBUKCGXg2aSSW4FVxpMUjnR9ELjb3vPHRSsIGfkLdrbu32bY-5mGXKDufZBoz7bFrJtey6CqhK21XqUsw54Wh2aVpsOhgG5hG7WbGbit38wW6gmt485e-HBf0_y1_OVcBXQa5fYYvJ3MR9CrXz_2IfAA7eklI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2739744002</pqid></control><display><type>article</type><title>The comparison of prognoses between total and distal gastrectomy for gastric cancer in elderly patients ≥ 80 years old</title><source>MEDLINE</source><source>SpringerNature Journals</source><creator>Endo, Shunji ; Yamatsuji, Tomoki ; Fujiwara, Yoshinori ; Higashida, Masaharu ; Kubota, Hisako ; Tanaka, Hironori ; Ito, Yoshitomo ; Okada, Toshimasa ; Yoshiatsu, Kazuhiko ; Ueno, Tomio</creator><creatorcontrib>Endo, Shunji ; Yamatsuji, Tomoki ; Fujiwara, Yoshinori ; Higashida, Masaharu ; Kubota, Hisako ; Tanaka, Hironori ; Ito, Yoshitomo ; Okada, Toshimasa ; Yoshiatsu, Kazuhiko ; Ueno, Tomio</creatorcontrib><description>Purpose
In Japan, the number of distal gastrectomy for patients ≥ 80 years old is increasing, whereas that of total gastrectomy is decreasing. Surgeons seem to avoid total gastrectomy for elderly patients. Total gastrectomy is reported to have a poorer prognosis than distal gastrectomy, and postoperative pneumonia may be involved in the cause.
Methods
The medical records of 39 and 108 patients ≥ 80 years old who underwent total and distal gastrectomy, respectively, at 2 affiliated institutions between 2010 and 2019 were retrospectively reviewed. Prognoses were compared between the two groups, focusing on death from pneumonia.
Results
The median overall survival time after total and distal gastrectomy was 21.3 and 74.1 months, respectively, with a significantly poorer prognosis after total gastrectomy than after distal gastrectomy (
p
< 0.01, hazard ratio [HR] 2.20, 95% confidence interval [CI] 1.37–3.53). The gastric cancer-specific survival time was significantly worse after total gastrectomy than after distal gastrectomy (
p
< 0.01, HR 2.73, 95% CI 1.29–5.79). The pneumonia-specific survival time was also significantly worse after total gastrectomy than after distal gastrectomy (
p
= 0.01, HR 3.44, 95% CI 1.25–9.48).
Conclusions
Patients who underwent total gastrectomy had a poorer prognosis than those who underwent distal gastrectomy, because many patients died of pneumonia early after total gastrectomy.</description><identifier>ISSN: 0941-1291</identifier><identifier>EISSN: 1436-2813</identifier><identifier>DOI: 10.1007/s00595-022-02599-0</identifier><identifier>PMID: 36418575</identifier><language>eng</language><publisher>Singapore: Springer Nature Singapore</publisher><subject>Aged ; Aged, 80 and over ; Gastrectomy - adverse effects ; Humans ; Medicine ; Medicine & Public Health ; Original Article ; Pneumonia - epidemiology ; Pneumonia - etiology ; Prognosis ; Retrospective Studies ; Stomach Neoplasms ; Surgery ; Surgical Oncology</subject><ispartof>Surgery today (Tokyo, Japan), 2023-05, Vol.53 (5), p.569-577</ispartof><rights>The Author(s) under exclusive licence to Springer Nature Singapore Pte Ltd. 2022. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2022. The Author(s) under exclusive licence to Springer Nature Singapore Pte Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c371t-296878d6e6cba0143b6c3e00e6e9058b917863a63896b7cdf6569e5d4d04761b3</citedby><cites>FETCH-LOGICAL-c371t-296878d6e6cba0143b6c3e00e6e9058b917863a63896b7cdf6569e5d4d04761b3</cites><orcidid>0000-0003-0720-4156</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00595-022-02599-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00595-022-02599-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36418575$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Endo, Shunji</creatorcontrib><creatorcontrib>Yamatsuji, Tomoki</creatorcontrib><creatorcontrib>Fujiwara, Yoshinori</creatorcontrib><creatorcontrib>Higashida, Masaharu</creatorcontrib><creatorcontrib>Kubota, Hisako</creatorcontrib><creatorcontrib>Tanaka, Hironori</creatorcontrib><creatorcontrib>Ito, Yoshitomo</creatorcontrib><creatorcontrib>Okada, Toshimasa</creatorcontrib><creatorcontrib>Yoshiatsu, Kazuhiko</creatorcontrib><creatorcontrib>Ueno, Tomio</creatorcontrib><title>The comparison of prognoses between total and distal gastrectomy for gastric cancer in elderly patients ≥ 80 years old</title><title>Surgery today (Tokyo, Japan)</title><addtitle>Surg Today</addtitle><addtitle>Surg Today</addtitle><description>Purpose
In Japan, the number of distal gastrectomy for patients ≥ 80 years old is increasing, whereas that of total gastrectomy is decreasing. Surgeons seem to avoid total gastrectomy for elderly patients. Total gastrectomy is reported to have a poorer prognosis than distal gastrectomy, and postoperative pneumonia may be involved in the cause.
Methods
The medical records of 39 and 108 patients ≥ 80 years old who underwent total and distal gastrectomy, respectively, at 2 affiliated institutions between 2010 and 2019 were retrospectively reviewed. Prognoses were compared between the two groups, focusing on death from pneumonia.
Results
The median overall survival time after total and distal gastrectomy was 21.3 and 74.1 months, respectively, with a significantly poorer prognosis after total gastrectomy than after distal gastrectomy (
p
< 0.01, hazard ratio [HR] 2.20, 95% confidence interval [CI] 1.37–3.53). The gastric cancer-specific survival time was significantly worse after total gastrectomy than after distal gastrectomy (
p
< 0.01, HR 2.73, 95% CI 1.29–5.79). The pneumonia-specific survival time was also significantly worse after total gastrectomy than after distal gastrectomy (
p
= 0.01, HR 3.44, 95% CI 1.25–9.48).
Conclusions
Patients who underwent total gastrectomy had a poorer prognosis than those who underwent distal gastrectomy, because many patients died of pneumonia early after total gastrectomy.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Gastrectomy - adverse effects</subject><subject>Humans</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Original Article</subject><subject>Pneumonia - epidemiology</subject><subject>Pneumonia - etiology</subject><subject>Prognosis</subject><subject>Retrospective Studies</subject><subject>Stomach Neoplasms</subject><subject>Surgery</subject><subject>Surgical Oncology</subject><issn>0941-1291</issn><issn>1436-2813</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kD1uFTEUhS1ERB4JG6BALmkmXI9n_FOiiJ9IkWiS2vLYdx4TzdgP20_oFUhpswsaNsJSspI4TKCkuL62fM6RzkfIawZnDEC-ywC97hto2zq91g08IxvWcdG0ivHnZAO6Yw1rNTsmL3O-AWg7BfCCHHPRMdXLfkN-XH1F6uKys2nKMdA40l2K2xAzZjpg-Y4YaInFztQGT_2UH69bm0tCV-JyoGNM63ty1NngMNEpUJw9pvlAd7ZMGEq-v727v_tVTwW_fx7Qpkzj7E_J0WjnjK-e9gm5_vjh6vxzc_nl08X5-8vGcclK02qhpPIChRss1IaDcBwBUKCGXg2aSSW4FVxpMUjnR9ELjb3vPHRSsIGfkLdrbu32bY-5mGXKDufZBoz7bFrJtey6CqhK21XqUsw54Wh2aVpsOhgG5hG7WbGbit38wW6gmt485e-HBf0_y1_OVcBXQa5fYYvJ3MR9CrXz_2IfAA7eklI</recordid><startdate>20230501</startdate><enddate>20230501</enddate><creator>Endo, Shunji</creator><creator>Yamatsuji, Tomoki</creator><creator>Fujiwara, Yoshinori</creator><creator>Higashida, Masaharu</creator><creator>Kubota, Hisako</creator><creator>Tanaka, Hironori</creator><creator>Ito, Yoshitomo</creator><creator>Okada, Toshimasa</creator><creator>Yoshiatsu, Kazuhiko</creator><creator>Ueno, Tomio</creator><general>Springer Nature Singapore</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-0720-4156</orcidid></search><sort><creationdate>20230501</creationdate><title>The comparison of prognoses between total and distal gastrectomy for gastric cancer in elderly patients ≥ 80 years old</title><author>Endo, Shunji ; Yamatsuji, Tomoki ; Fujiwara, Yoshinori ; Higashida, Masaharu ; Kubota, Hisako ; Tanaka, Hironori ; Ito, Yoshitomo ; Okada, Toshimasa ; Yoshiatsu, Kazuhiko ; Ueno, Tomio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c371t-296878d6e6cba0143b6c3e00e6e9058b917863a63896b7cdf6569e5d4d04761b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Gastrectomy - adverse effects</topic><topic>Humans</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Original Article</topic><topic>Pneumonia - epidemiology</topic><topic>Pneumonia - etiology</topic><topic>Prognosis</topic><topic>Retrospective Studies</topic><topic>Stomach Neoplasms</topic><topic>Surgery</topic><topic>Surgical Oncology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Endo, Shunji</creatorcontrib><creatorcontrib>Yamatsuji, Tomoki</creatorcontrib><creatorcontrib>Fujiwara, Yoshinori</creatorcontrib><creatorcontrib>Higashida, Masaharu</creatorcontrib><creatorcontrib>Kubota, Hisako</creatorcontrib><creatorcontrib>Tanaka, Hironori</creatorcontrib><creatorcontrib>Ito, Yoshitomo</creatorcontrib><creatorcontrib>Okada, Toshimasa</creatorcontrib><creatorcontrib>Yoshiatsu, Kazuhiko</creatorcontrib><creatorcontrib>Ueno, Tomio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Surgery today (Tokyo, Japan)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Endo, Shunji</au><au>Yamatsuji, Tomoki</au><au>Fujiwara, Yoshinori</au><au>Higashida, Masaharu</au><au>Kubota, Hisako</au><au>Tanaka, Hironori</au><au>Ito, Yoshitomo</au><au>Okada, Toshimasa</au><au>Yoshiatsu, Kazuhiko</au><au>Ueno, Tomio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The comparison of prognoses between total and distal gastrectomy for gastric cancer in elderly patients ≥ 80 years old</atitle><jtitle>Surgery today (Tokyo, Japan)</jtitle><stitle>Surg Today</stitle><addtitle>Surg Today</addtitle><date>2023-05-01</date><risdate>2023</risdate><volume>53</volume><issue>5</issue><spage>569</spage><epage>577</epage><pages>569-577</pages><issn>0941-1291</issn><eissn>1436-2813</eissn><abstract>Purpose
In Japan, the number of distal gastrectomy for patients ≥ 80 years old is increasing, whereas that of total gastrectomy is decreasing. Surgeons seem to avoid total gastrectomy for elderly patients. Total gastrectomy is reported to have a poorer prognosis than distal gastrectomy, and postoperative pneumonia may be involved in the cause.
Methods
The medical records of 39 and 108 patients ≥ 80 years old who underwent total and distal gastrectomy, respectively, at 2 affiliated institutions between 2010 and 2019 were retrospectively reviewed. Prognoses were compared between the two groups, focusing on death from pneumonia.
Results
The median overall survival time after total and distal gastrectomy was 21.3 and 74.1 months, respectively, with a significantly poorer prognosis after total gastrectomy than after distal gastrectomy (
p
< 0.01, hazard ratio [HR] 2.20, 95% confidence interval [CI] 1.37–3.53). The gastric cancer-specific survival time was significantly worse after total gastrectomy than after distal gastrectomy (
p
< 0.01, HR 2.73, 95% CI 1.29–5.79). The pneumonia-specific survival time was also significantly worse after total gastrectomy than after distal gastrectomy (
p
= 0.01, HR 3.44, 95% CI 1.25–9.48).
Conclusions
Patients who underwent total gastrectomy had a poorer prognosis than those who underwent distal gastrectomy, because many patients died of pneumonia early after total gastrectomy.</abstract><cop>Singapore</cop><pub>Springer Nature Singapore</pub><pmid>36418575</pmid><doi>10.1007/s00595-022-02599-0</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0003-0720-4156</orcidid></addata></record> |
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| ispartof | Surgery today (Tokyo, Japan), 2023-05, Vol.53 (5), p.569-577 |
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| language | eng |
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| source | MEDLINE; SpringerNature Journals |
| subjects | Aged Aged, 80 and over Gastrectomy - adverse effects Humans Medicine Medicine & Public Health Original Article Pneumonia - epidemiology Pneumonia - etiology Prognosis Retrospective Studies Stomach Neoplasms Surgery Surgical Oncology |
| title | The comparison of prognoses between total and distal gastrectomy for gastric cancer in elderly patients ≥ 80 years old |
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