The relationship between LRP5 rs556442 and rs638051 polymorphisms and mutations and their influence on bone metabolism in postmenopausal Xinjiang women with type 2 diabetes

The Wnt/β-catenin signaling pathway plays a crucial role in bone development and metabolism. The low-density lipoprotein receptor-related protein 5 (LRP5), an important receptor in the Wnt signaling pathway, promotes the osteogenesis of osteoblasts and curbs bone resorption by osteoclasts. To determ...

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Veröffentlicht in:	Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023-04, Vol.32 (4), p.433-439
Hauptverfasser:	Li, Jun, Song, Minli, Li, Siyuan, Wang, Xiling, Zhao, Huirong, Hou, Zexin
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone Density - genetics Diabetes Mellitus, Type 2 Female Humans Low Density Lipoprotein Receptor-Related Protein-5 - genetics Lumbar Vertebrae Mutation Postmenopause - genetics
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