Preclinical Observations of Systemic and Ocular Antidrug Antibody Response to Intravitreally Administered Drugs

Intravitreally administered biotherapeutics can elicit local and systemic immune responses with potentially serious clinical consequences. However, little is known about the mechanisms of ocular antidrug immune response, the incidence of ocular antidrug antibodies (ADAs), and the relationship betwee...

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Veröffentlicht in:	The AAPS journal 2022-11, Vol.25 (1), p.2-2, Article 2
Hauptverfasser:	Wessels, Uwe, Zadak, Markus, Weidmann, Anja Manuela, Stuchly, Thomas, Stubenrauch, Kay-Gunnar
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Antibodies Antibody Formation Biochemistry Biomedical and Life Sciences Biomedicine Biotechnology Eye Immune response Macaca fascicularis Pharmaceutical Preparations Pharmacology/Toxicology Pharmacy Research Article Swine Swine, Miniature Viral antibodies
Online-Zugang:	Volltext
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