Novel low‐grade renal spindle cell neoplasm with HEY1::NCOA2 fusion that is distinct from mesenchymal chondrosarcoma

HEY1‐NCOA2 fusion is most described in mesenchymal chondrosarcoma. This is the first case report of a primary renal spindle cell neoplasm of uncertain malignant potential with a HEY1::NCOA2 fusion identified by Fusionplex RNA‐sequencing that is histologically distinct from mesenchymal chondrosarcoma...

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Veröffentlicht in:	Genes chromosomes & cancer 2023-03, Vol.62 (3), p.171-175
Hauptverfasser:	Miller, Timothy Isaac, Mantilla, Jose G., Wang, Wenjing, Liu, Yajuan J., Tretiakova, Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Basic Helix-Loop-Helix Transcription Factors - genetics Bone cancer Bone Neoplasms - genetics Bone Neoplasms - pathology Calcification Cell Cycle Proteins - genetics Cell Cycle Proteins - metabolism Chondrosarcoma Chondrosarcoma, Mesenchymal - genetics Chondrosarcoma, Mesenchymal - pathology Chondrosarcoma, Mesenchymal - surgery Collagen Cytology Female HEY1 Humans kidney sarcoma Kidneys mesenchymal chondrosarcoma Mesenchyme NCOA2 Nephrectomy Nuclear Receptor Coactivator 2 - genetics renal fusion sarcoma renal spindle cell neoplasm Sarcoma Stroma
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