Concise synthesis of amino acid component of amicoumacins via dihydrooxazine formation through intramolecular conjugate addition

Amicoumacins are a family of antibiotics with a variety of important bioactivities. A concise and efficient method was developed for synthesizing the amino acid component of amicoumacins via the corresponding dihydrooxazine intermediate. The dihydrooxazine ring was formed with complete stereoselecti...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2023-01, Vol.87 (2), p.131-137
Hauptverfasser:	Matsushima, Yoshitaka, Ogawa, Yukako, Nishi, Katsuya, Nakata, Kyosuke
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids Anti-Bacterial Agents Cyclization Esters - chemistry
Online-Zugang:	Volltext
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