Deleterious effect in endothelin receptor–mediated coronary artery smooth muscle contractility in high-salt diet rats

High-salt diet has been suggested to increase the risk of heart disease. However, the mechanisms underlying coronary artery tension dysfunction caused by high-salt diet are unclear. Previous studies have shown that coronary artery spasm is often induced by endothelin-1 (ET-1) and thromboxane, leadin...

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Veröffentlicht in:	Nutrition, metabolism, and cardiovascular diseases metabolism, and cardiovascular diseases, 2023-01, Vol.33 (1), p.234-244
Hauptverfasser:	Xiao, Hui, Lu, Haoyang, Xue, Yangcheng, Jia, Zhuoran, Dai, Manyu, He, Ke, Zhao, Ren
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium Coronary artery Coronary Vessels Diet Endothelin-1 Endothelin-1 - metabolism Heart Diseases High-salt intake Muscle, Smooth, Vascular - metabolism Rats Receptors, Endothelin - metabolism Sodium Chloride, Dietary - adverse effects Store-operated calcium entry
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