Digoxin as an emerging therapy in noncardiac diseases

The cardiac glycoside (CG) digoxin is a generic drug approved for the treatment of heart failure and supraventricular arrhythmias. Over the past few decades, substantial strides have been made toward repurposing digoxin to treat various noncardiac diseases. Here, we evaluate recent insights into bas...

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Veröffentlicht in:	Trends in pharmacological sciences (Regular ed.) 2023-04, Vol.44 (4), p.199-203
Hauptverfasser:	Dashti, Farzaneh, Jamshed, Fatima, Ouyang, Xinshou, Mehal, Wajahat Z., Banini, Bubu A.
Format:	Artikel
Sprache:	eng
Schlagworte:	alcohol-associated steatohepatitis cancer Cardiac Glycosides digoxin Digoxin - pharmacology Digoxin - therapeutic use drug repurposing Heart Failure - drug therapy Humans Na,K-ATPase nonalcoholic steatohepatitis obesity Ouabain Sodium-Potassium-Exchanging ATPase - metabolism
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