Does Minimally Invasive Mitral Valve Repair Mean Less Postoperative Pain?
Rapid recovery after minimally invasive mitral valve (MV) repair has been demonstrated in many studies, but the issue of postoperative pain has not been fully elucidated. We evaluated pain scores and medication use in patients undergoing MV repair by minimally invasive surgery (MIS) and open sternot...
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Veröffentlicht in: | The Annals of thoracic surgery 2023-05, Vol.115 (5), p.1172-1178 |
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creator | Jahanian, Sepideh Arghami, Arman Wittwer, Erica D. King, Katherine S. Daly, Richard C. Dearani, Joseph A. Rowse, Phillip G. Crestanello, Juan A. Schaff, Hartzell V. |
description | Rapid recovery after minimally invasive mitral valve (MV) repair has been demonstrated in many studies, but the issue of postoperative pain has not been fully elucidated. We evaluated pain scores and medication use in patients undergoing MV repair by minimally invasive surgery (MIS) and open sternotomy (OS).
Between 2008 and 2019, 1332 patients underwent isolated MV repair by OS, and 913 underwent minimally invasive MV repair. After 1:1 propensity score matching, the study included 709 patients in each group. Opioid use was quantified as oral morphine equivalents in milligrams for each hospital day. The highest pain scores were collected from a visual analogue scale at 6-hour intervals. Predictive modeling was employed to compare pain medications and pain scores between the groups.
The postoperative median length of stay was 3 (3-4) and 5 (4-5) days for the MIS and OS groups, respectively (P < .001). The predicted geometric mean oral morphine equivalents demonstrated lower opioid use for the MIS group compared with the OS group for the first 4 days. However, the predicted mean pain score was higher in the first 24 hours for the MIS group compared with the OS group (4.7 [4.5-4.8] vs 4.4 [4.3-4.5], respectively, on a visual analogue scale of 0 to 10).
MV repair by MIS methods was associated with decreased opioid use but not with decreased postoperative pain scores. Possible explanations include the difference in incision site pain and subjective differences in postoperative pain expectations. |
doi_str_mv | 10.1016/j.athoracsur.2022.11.009 |
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Between 2008 and 2019, 1332 patients underwent isolated MV repair by OS, and 913 underwent minimally invasive MV repair. After 1:1 propensity score matching, the study included 709 patients in each group. Opioid use was quantified as oral morphine equivalents in milligrams for each hospital day. The highest pain scores were collected from a visual analogue scale at 6-hour intervals. Predictive modeling was employed to compare pain medications and pain scores between the groups.
The postoperative median length of stay was 3 (3-4) and 5 (4-5) days for the MIS and OS groups, respectively (P < .001). The predicted geometric mean oral morphine equivalents demonstrated lower opioid use for the MIS group compared with the OS group for the first 4 days. However, the predicted mean pain score was higher in the first 24 hours for the MIS group compared with the OS group (4.7 [4.5-4.8] vs 4.4 [4.3-4.5], respectively, on a visual analogue scale of 0 to 10).
MV repair by MIS methods was associated with decreased opioid use but not with decreased postoperative pain scores. Possible explanations include the difference in incision site pain and subjective differences in postoperative pain expectations.</description><identifier>ISSN: 0003-4975</identifier><identifier>EISSN: 1552-6259</identifier><identifier>DOI: 10.1016/j.athoracsur.2022.11.009</identifier><identifier>PMID: 36395877</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Analgesics, Opioid - therapeutic use ; Humans ; Minimally Invasive Surgical Procedures - methods ; Mitral Valve - surgery ; Morphine Derivatives - therapeutic use ; Opioid-Related Disorders - etiology ; Pain, Postoperative - drug therapy ; Retrospective Studies ; Treatment Outcome</subject><ispartof>The Annals of thoracic surgery, 2023-05, Vol.115 (5), p.1172-1178</ispartof><rights>2023</rights><rights>Copyright © 2023. Published by Elsevier Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c374t-ce5277348cac082a97888860ba02ec97077fdba59d3a72fc8286da3cf9d227e3</citedby><cites>FETCH-LOGICAL-c374t-ce5277348cac082a97888860ba02ec97077fdba59d3a72fc8286da3cf9d227e3</cites><orcidid>0000-0002-7398-0738 ; 0000-0002-3783-6982</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.athoracsur.2022.11.009$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3536,27903,27904,45974</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36395877$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Jahanian, Sepideh</creatorcontrib><creatorcontrib>Arghami, Arman</creatorcontrib><creatorcontrib>Wittwer, Erica D.</creatorcontrib><creatorcontrib>King, Katherine S.</creatorcontrib><creatorcontrib>Daly, Richard C.</creatorcontrib><creatorcontrib>Dearani, Joseph A.</creatorcontrib><creatorcontrib>Rowse, Phillip G.</creatorcontrib><creatorcontrib>Crestanello, Juan A.</creatorcontrib><creatorcontrib>Schaff, Hartzell V.</creatorcontrib><title>Does Minimally Invasive Mitral Valve Repair Mean Less Postoperative Pain?</title><title>The Annals of thoracic surgery</title><addtitle>Ann Thorac Surg</addtitle><description>Rapid recovery after minimally invasive mitral valve (MV) repair has been demonstrated in many studies, but the issue of postoperative pain has not been fully elucidated. We evaluated pain scores and medication use in patients undergoing MV repair by minimally invasive surgery (MIS) and open sternotomy (OS).
Between 2008 and 2019, 1332 patients underwent isolated MV repair by OS, and 913 underwent minimally invasive MV repair. After 1:1 propensity score matching, the study included 709 patients in each group. Opioid use was quantified as oral morphine equivalents in milligrams for each hospital day. The highest pain scores were collected from a visual analogue scale at 6-hour intervals. Predictive modeling was employed to compare pain medications and pain scores between the groups.
The postoperative median length of stay was 3 (3-4) and 5 (4-5) days for the MIS and OS groups, respectively (P < .001). The predicted geometric mean oral morphine equivalents demonstrated lower opioid use for the MIS group compared with the OS group for the first 4 days. However, the predicted mean pain score was higher in the first 24 hours for the MIS group compared with the OS group (4.7 [4.5-4.8] vs 4.4 [4.3-4.5], respectively, on a visual analogue scale of 0 to 10).
MV repair by MIS methods was associated with decreased opioid use but not with decreased postoperative pain scores. Possible explanations include the difference in incision site pain and subjective differences in postoperative pain expectations.</description><subject>Analgesics, Opioid - therapeutic use</subject><subject>Humans</subject><subject>Minimally Invasive Surgical Procedures - methods</subject><subject>Mitral Valve - surgery</subject><subject>Morphine Derivatives - therapeutic use</subject><subject>Opioid-Related Disorders - etiology</subject><subject>Pain, Postoperative - drug therapy</subject><subject>Retrospective Studies</subject><subject>Treatment Outcome</subject><issn>0003-4975</issn><issn>1552-6259</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtPwzAMgCMEYmPwF1CPXFryWJvkhGC8Jm1iQhPXyEtdkalrR9JN2r8n0wYc8cVy8tmWP0ISRjNGWXG7zKD7bD3YsPEZp5xnjGWU6hPSZ3nO04Ln-pT0KaUiHWqZ98hFCMtY8vh9TnqiEDpXUvbJ-LHFkExd41ZQ17tk3GwhuC3Gp85DnXxAHYt3XIPzyRShSSYYQjJrQ9eu0UO3Z2fgmrtLclZBHfDqmAdk_vw0H72mk7eX8eh-klohh11qMedSiqGyYKnioKWKUdAFUI5WSyplVS4g16UAySuruCpKELbSJecSxYDcHMauffu1wdCZlQsW6xoabDfBcCkU03QoVUTVAbW-DcFjZdY-nul3hlGz92iW5s-j2Xs0jJnoMbZeH7dsFissfxt_xEXg4QBgPHXr0JtgHTYWS-fRdqZs3f9bvgFWT4kq</recordid><startdate>202305</startdate><enddate>202305</enddate><creator>Jahanian, Sepideh</creator><creator>Arghami, Arman</creator><creator>Wittwer, Erica D.</creator><creator>King, Katherine S.</creator><creator>Daly, Richard C.</creator><creator>Dearani, Joseph A.</creator><creator>Rowse, Phillip G.</creator><creator>Crestanello, Juan A.</creator><creator>Schaff, Hartzell V.</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-7398-0738</orcidid><orcidid>https://orcid.org/0000-0002-3783-6982</orcidid></search><sort><creationdate>202305</creationdate><title>Does Minimally Invasive Mitral Valve Repair Mean Less Postoperative Pain?</title><author>Jahanian, Sepideh ; Arghami, Arman ; Wittwer, Erica D. ; King, Katherine S. ; Daly, Richard C. ; Dearani, Joseph A. ; Rowse, Phillip G. ; Crestanello, Juan A. ; Schaff, Hartzell V.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c374t-ce5277348cac082a97888860ba02ec97077fdba59d3a72fc8286da3cf9d227e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Analgesics, Opioid - therapeutic use</topic><topic>Humans</topic><topic>Minimally Invasive Surgical Procedures - methods</topic><topic>Mitral Valve - surgery</topic><topic>Morphine Derivatives - therapeutic use</topic><topic>Opioid-Related Disorders - etiology</topic><topic>Pain, Postoperative - drug therapy</topic><topic>Retrospective Studies</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jahanian, Sepideh</creatorcontrib><creatorcontrib>Arghami, Arman</creatorcontrib><creatorcontrib>Wittwer, Erica D.</creatorcontrib><creatorcontrib>King, Katherine S.</creatorcontrib><creatorcontrib>Daly, Richard C.</creatorcontrib><creatorcontrib>Dearani, Joseph A.</creatorcontrib><creatorcontrib>Rowse, Phillip G.</creatorcontrib><creatorcontrib>Crestanello, Juan A.</creatorcontrib><creatorcontrib>Schaff, Hartzell V.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Annals of thoracic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jahanian, Sepideh</au><au>Arghami, Arman</au><au>Wittwer, Erica D.</au><au>King, Katherine S.</au><au>Daly, Richard C.</au><au>Dearani, Joseph A.</au><au>Rowse, Phillip G.</au><au>Crestanello, Juan A.</au><au>Schaff, Hartzell V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Does Minimally Invasive Mitral Valve Repair Mean Less Postoperative Pain?</atitle><jtitle>The Annals of thoracic surgery</jtitle><addtitle>Ann Thorac Surg</addtitle><date>2023-05</date><risdate>2023</risdate><volume>115</volume><issue>5</issue><spage>1172</spage><epage>1178</epage><pages>1172-1178</pages><issn>0003-4975</issn><eissn>1552-6259</eissn><abstract>Rapid recovery after minimally invasive mitral valve (MV) repair has been demonstrated in many studies, but the issue of postoperative pain has not been fully elucidated. We evaluated pain scores and medication use in patients undergoing MV repair by minimally invasive surgery (MIS) and open sternotomy (OS).
Between 2008 and 2019, 1332 patients underwent isolated MV repair by OS, and 913 underwent minimally invasive MV repair. After 1:1 propensity score matching, the study included 709 patients in each group. Opioid use was quantified as oral morphine equivalents in milligrams for each hospital day. The highest pain scores were collected from a visual analogue scale at 6-hour intervals. Predictive modeling was employed to compare pain medications and pain scores between the groups.
The postoperative median length of stay was 3 (3-4) and 5 (4-5) days for the MIS and OS groups, respectively (P < .001). The predicted geometric mean oral morphine equivalents demonstrated lower opioid use for the MIS group compared with the OS group for the first 4 days. However, the predicted mean pain score was higher in the first 24 hours for the MIS group compared with the OS group (4.7 [4.5-4.8] vs 4.4 [4.3-4.5], respectively, on a visual analogue scale of 0 to 10).
MV repair by MIS methods was associated with decreased opioid use but not with decreased postoperative pain scores. Possible explanations include the difference in incision site pain and subjective differences in postoperative pain expectations.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>36395877</pmid><doi>10.1016/j.athoracsur.2022.11.009</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-7398-0738</orcidid><orcidid>https://orcid.org/0000-0002-3783-6982</orcidid></addata></record> |
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subjects | Analgesics, Opioid - therapeutic use Humans Minimally Invasive Surgical Procedures - methods Mitral Valve - surgery Morphine Derivatives - therapeutic use Opioid-Related Disorders - etiology Pain, Postoperative - drug therapy Retrospective Studies Treatment Outcome |
title | Does Minimally Invasive Mitral Valve Repair Mean Less Postoperative Pain? |
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