14-fold increased prevalence of rare glucokinase gene variant carriers in unselected Danish patients with newly diagnosed type 2 diabetes

Rare variants in the glucokinase gene (GCK) cause Maturity-Onset Diabetes of the Young (MODY2/GCK-MODY). We investigated the prevalence of GCK variants, phenotypic characteristics, micro- and macrovascular disease at baseline and follow-up, and treatment among individuals with and without pathogenic...

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Veröffentlicht in:	Diabetes research and clinical practice 2022-12, Vol.194, p.110159-110159, Article 110159
Hauptverfasser:	Gjesing, Anette P, Engelbrechtsen, Line, Cathrine B Thuesen, Anne, Have, Christian T, Hollensted, Mette, Grarup, Niels, Linneberg, Allan, Steen Nielsen, Jens, Christensen, Lotte B, Thomsen, Reimar W, Johansson, Kristoffer E, Cagiada, Matteo, Gersing, Sarah, Hartmann-Petersen, Rasmus, Lindorff-Larsen, Kresten, Vaag, Allan, Sørensen, Henrik T, Brandslund, Ivan, Beck-Nielsen, Henning, Pedersen, Oluf, Rungby, Jørgen, Hansen, Torben
Format:	Artikel
Sprache:	eng
Schlagworte:	Cross-Sectional Studies Denmark Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - genetics Glucokinase - genetics Heterozygote Humans Mutation
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