Copper nanoclusters on specific-primer PCR fragments with magnetic capture for the label-free fluorescent sensing of the T315I single nucleotide variant in the BCR – ABL1 gene

In this study, a simple and facile procedure using the all or none formation of double-stranded DNA-templated copper nanoclusters on specific-primer PCR fragments was designed to fluorescently identify the T315I single nucleotide variant on the BCR – ABL1 gene. Chronic myeloid leukaemia (CML), a dis...

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Veröffentlicht in:	Analyst (London) 2022-12, Vol.147 (24), p.5732-5738
Hauptverfasser:	Lai, Ke-Peng, Su, Yu-Chen, Fu, Bo-Siang, Lin, Kung-Hung, Kou, Hwang-Shang, Wang, Chun-Chi
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding sites Copper Deoxyribonucleic acid DNA Fluorescence Fragments Kinases Leukemia Mutation Nanoclusters Nucleotides Tyrosine
Online-Zugang:	Volltext
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