The combined action of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor increases proinflammatory mediator production by cardiomyocytes and vascular endothelial cells

Cardiomyopathy is the most serious complication of chronic Chagas disease, caused by infection with the protozoan Trypanosoma cruzi. Exacerbated inflammation of the myocardium constitutes a major pathologic component of the disease. In the myocardial microenvironment, parasite antigens and host infl...

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Veröffentlicht in:	Microbial pathogenesis 2022-12, Vol.173, p.105881-105881, Article 105881
Hauptverfasser:	Rigazio, Cristina S., Mariz-Ponte, Nilo, Pérez Caballero, Eugenia, Penas, Federico N., Goren, Nora B., Santamaría, Miguel H., Corral, Ricardo S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Chagas cardiomyopathy Eicosanoid production Glycoinositolphospholipid Inflammatory mediators Macrophage migration inhibitory factor Trypanosoma cruzi
Online-Zugang:	Volltext
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