Physician- and patient-reported symptom concordance and association with quality of life in hepatocellular carcinoma

To investigate the association of discordance in patient- and physician-reported symptoms on health-related quality of life (HRQoL) in hepatocellular carcinoma (HCC). Data were drawn from a point-in-time survey of physicians and patients conducted in Germany, Italy and Spain (October 2018 – January...

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Veröffentlicht in:	Future oncology (London, England) England), 2022-10, Vol.18 (33), p.3727-3740
Hauptverfasser:	Leith, Andrea, Kiiskinen, Urpo, Girvan, Allicia C, Jen, Min-Hua, Khela, Keerun, Rider, Alex, Massey, Lucy, Piercy, James
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma, Hepatocellular - diagnosis Carcinoma, Hepatocellular - epidemiology Carcinoma, Hepatocellular - therapy concordance health-related quality of life hepatocellular carcinoma Humans Liver Neoplasms - complications Liver Neoplasms - diagnosis Liver Neoplasms - therapy Pain Patient Reported Outcome Measures Physicians Quality of Life real-world survey Surveys and Questionnaires symptoms
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container_title	Future oncology (London, England)
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creator	Leith, Andrea Kiiskinen, Urpo Girvan, Allicia C Jen, Min-Hua Khela, Keerun Rider, Alex Massey, Lucy Piercy, James
description	To investigate the association of discordance in patient- and physician-reported symptoms on health-related quality of life (HRQoL) in hepatocellular carcinoma (HCC). Data were drawn from a point-in-time survey of physicians and patients conducted in Germany, Italy and Spain (October 2018 – January 2019). Physicians and their consulting patients independently reported baseline characteristics, symptoms, treatment history and satisfaction, and HRQoL derived using the Functional Assessment of Cancer Therapy-Hepatobiliary (FACT-Hep) questionnaire. Of 486 patients analysed, tiredness (73.3%, 73.7%), pain/aches (67.7%, 66.9%) and weight/appetite loss (54.3%, 53.7%) were the most common and concordant patient and physician-reported symptom domains, respectively. The symptom domains showing the largest discordance were reflux/indigestion (14.6%, 5.1%), neurological (11.9%, 5.6%), dermatological (9.3%, 6.2%) symptoms and jaundice (4.7%, 10.3%). Reduced HRQoL was observed with increasing symptom-reporting discordance. Further studies should investigate how symptom-reporting discordance influences patient satisfaction and HRQoL.
doi_str_mv	10.2217/fon-2022-0202
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Further studies should investigate how symptom-reporting discordance influences patient satisfaction and HRQoL.</description><identifier>ISSN: 1479-6694</identifier><identifier>EISSN: 1744-8301</identifier><identifier>DOI: 10.2217/fon-2022-0202</identifier><identifier>PMID: 36377818</identifier><language>eng</language><publisher>England: Future Medicine Ltd</publisher><subject>Carcinoma, Hepatocellular - diagnosis ; Carcinoma, Hepatocellular - epidemiology ; Carcinoma, Hepatocellular - therapy ; concordance ; health-related quality of life ; hepatocellular carcinoma ; Humans ; Liver Neoplasms - complications ; Liver Neoplasms - diagnosis ; Liver Neoplasms - therapy ; Pain ; Patient Reported Outcome Measures ; Physicians ; Quality of Life ; real-world survey ; Surveys and Questionnaires ; symptoms</subject><ispartof>Future oncology (London, England), 2022-10, Vol.18 (33), p.3727-3740</ispartof><rights>2022 Adelphi Real World</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c338t-24bb8ac9740e83a1ddb60fd872d9f4c0dda61de94265b1bb384038fcf7a861323</cites><orcidid>0000-0002-4916-0107 ; 0000-0002-8656-002X ; 0000-0003-0394-2303 ; 0000-0002-7869-3543 ; 0000-0003-3487-5609 ; 0000-0002-1147-5306 ; 0000-0003-0791-940X ; 0000-0001-7015-1021</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36377818$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Leith, Andrea</creatorcontrib><creatorcontrib>Kiiskinen, Urpo</creatorcontrib><creatorcontrib>Girvan, Allicia C</creatorcontrib><creatorcontrib>Jen, Min-Hua</creatorcontrib><creatorcontrib>Khela, Keerun</creatorcontrib><creatorcontrib>Rider, Alex</creatorcontrib><creatorcontrib>Massey, Lucy</creatorcontrib><creatorcontrib>Piercy, James</creatorcontrib><title>Physician- and patient-reported symptom concordance and association with quality of life in hepatocellular carcinoma</title><title>Future oncology (London, England)</title><addtitle>Future Oncol</addtitle><description>To investigate the association of discordance in patient- and physician-reported symptoms on health-related quality of life (HRQoL) in hepatocellular carcinoma (HCC). 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subjects	Carcinoma, Hepatocellular - diagnosis Carcinoma, Hepatocellular - epidemiology Carcinoma, Hepatocellular - therapy concordance health-related quality of life hepatocellular carcinoma Humans Liver Neoplasms - complications Liver Neoplasms - diagnosis Liver Neoplasms - therapy Pain Patient Reported Outcome Measures Physicians Quality of Life real-world survey Surveys and Questionnaires symptoms
title	Physician- and patient-reported symptom concordance and association with quality of life in hepatocellular carcinoma
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