Real world molecular characterisation and clonal evolution of acute myeloid leukaemia reveals therapeutic opportunities and challenges

Acute myeloid leukaemia (AML) is an aggressive haematological malignancy with poor prognosis. Increasing understanding of the molecular mechanisms driving clonal proliferation has resulted in advancements in classification and available therapeutic targets. Fms-related tyrosine kinase 3 (FLT3) mutat...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Pathology 2023-02, Vol.55 (1), p.64-70
Hauptverfasser:	Nelles, Ricky, Seymour, Louise, Richmond, Joshua, Lane, Steven
Format:	Artikel
Sprache:	eng
Schlagworte:	FLT3 genetics leukaemia molecular Myeloid
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!