Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid

Macrophages are important players in the maintenance of tissue homeostasis 1 . Perivascular and leptomeningeal macrophages reside near the central nervous system (CNS) parenchyma 2 , and their role in CNS physiology has not been sufficiently well studied. Given their continuous interaction with the...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 2022-11, Vol.611 (7936), p.585-593
Hauptverfasser:	Drieu, Antoine, Du, Siling, Storck, Steffen E., Rustenhoven, Justin, Papadopoulos, Zachary, Dykstra, Taitea, Zhong, Fenghe, Kim, Kyungdeok, Blackburn, Susan, Mamuladze, Tornike, Harari, Oscar, Karch, Celeste M., Bateman, Randall J., Perrin, Richard, Farlow, Martin, Chhatwal, Jasmeer, Hu, Song, Randolph, Gwendalyn J., Smirnov, Igor, Kipnis, Jonathan
Format:	Artikel
Sprache:	eng
Schlagworte:	14/19 14/28 14/34 14/63 59 59/57 631/250/371 631/378/371 Aging Aging - metabolism Alzheimer Disease - metabolism Alzheimer's disease Animals Antigens Blocking Brain Brain - metabolism CD163 antigen Central nervous system Central Nervous System - cytology Central Nervous System - metabolism Cerebrospinal fluid Cerebrospinal Fluid - metabolism Colony-stimulating factor Cytokines Depletion Dynamics Endocytosis Extracellular matrix Extracellular Matrix Proteins - metabolism Flow cytometry Gene expression Gene sequencing Humanities and Social Sciences Humans Interferon Interferon-gamma - metabolism Macrophage colony-stimulating factor Macrophages Macrophages - physiology Meninges Meninges - cytology Mice multidisciplinary Neurodegenerative diseases Parenchymal Tissue - cytology Phagocytosis Pharmacology Physiology Proteins Rheology Scavenger receptors Science Science (multidisciplinary) Signal transduction
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!