Engineering SHP2 Phosphatase for Optical Control

Signal transduction pathways are responsible for maintaining cellular functions, including proliferation, differentiation, apoptosis, and cell cycle progression. These pathways are maintained through the propagation of phosphorylation signals by protein kinases, as well as the removal of phosphoryla...

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Veröffentlicht in:	Biochemistry (Easton) 2022-12, Vol.61 (23), p.2687-2697
Hauptverfasser:	Ryan, Amy, Janosko, Chasity P., Courtney, Taylor M., Deiters, Alexander
Format:	Artikel
Sprache:	eng
Schlagworte:	Phosphorylation Protein Tyrosine Phosphatase, Non-Receptor Type 11 - genetics SH2 Domain-Containing Protein Tyrosine Phosphatases Signal Transduction src Homology Domains
Online-Zugang:	Volltext
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