Intermolecular and Intramolecular Priming Co-directed Synergistic Multi-strand Displacement Amplification Empowers Ultrasensitive Determination of microRNAs

The construction of isothermal nucleic acid amplification systems with extremely high signal amplification abilities is of great importance for biomarker detection and disease diagnosis. Herein, for the first time, we proposed an intermolecular and intramolecular priming co-directed synergistic mult...

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Veröffentlicht in:	Analytical chemistry (Washington) 2022-11, Vol.94 (46), p.16132-16141
Hauptverfasser:	Xia, Juan, Liu, Zhaoqiang, Gao, Shulin, Wang, Qi, Xu, Jianguo, Wu, Hai
Format:	Artikel
Sprache:	eng
Schlagworte:	Amplification Biomarkers Biosensing Techniques Chemistry Diagnosis Displacement MicroRNAs MicroRNAs - analysis miRNA Nucleic Acid Amplification Techniques - methods Nucleic acids Priming Qualitative analysis Replication Ribonucleic acid RNA
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