Inhibition of anandamide breakdown reduces pain and restores LTP and monoamine levels in the rat hippocampus via the CB1 receptor following osteoarthritis

Chronic pain is a persistent, complex condition that contributes to impaired mood, anxiety and emotional problems. Osteoarthritis (OA) is one of the major causes of chronic pain in adults and elderly people. A substantial body of evidence demonstrate that hippocampal neural circuits, especially mono...

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Veröffentlicht in:	Neuropharmacology 2023-01, Vol.222, p.109304-109304, Article 109304
Hauptverfasser:	Kędziora, Marta, Boccella, Serena, Marabese, Ida, Mlost, Jakub, Infantino, Rosmara, Maione, Sabatino, Starowicz, Katarzyna
Format:	Artikel
Sprache:	eng
Schlagworte:	Anandamide Chronic pain Dopamine Hippocampus Long term potentiation Osteoarthritis
Online-Zugang:	Volltext
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