Molecular characteristics of pediatric nasopharyngeal carcinoma using whole-exome sequencing

•We first reported the somatic and germline genetic aberrations in pNPC.•Patients with pNPC exhibited high level of PD-L1 expression.•Our results provide a deeper understanding of molecular genetics of pNPC. While a number of genetic and epigenetic events contributing to adult nasopharyngeal carcino...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oral oncology 2022-12, Vol.135, p.106218-106218, Article 106218
Hauptverfasser:	Wu, Bian, Shen, Liangfang, Peng, Gang, Li, Yingqiang, Zhou, Zhiyuan, Li, Jingao, Huang, Xiaodong, Zhou, Qin, Jiang, Hongguo, Huang, Jing, Ding, Qian, Zhang, Zhanjie, Qin, You, Hong, Xiaohua, Shi, Liangliang, Zou, Zhenwei, Yao, Jing, Zhang, Jing, Liu, Danni, Wan, Chao, Wu, Gang, Song, Lele, Chen, Shifu, Yi, Junlin, Yang, Kunyu
Format:	Artikel
Sprache:	eng
Schlagworte:	B7-H1 Antigen - metabolism Child Exome Sequencing Female Humans Male Mutation Nasopharyngeal Carcinoma - genetics Nasopharyngeal Carcinoma - pathology Nasopharyngeal Neoplasms - genetics Nasopharyngeal Neoplasms - pathology Neoplasm Recurrence, Local Pediatric cancer Pediatric nasopharyngeal carcinoma Rare cancer RNA-Binding Proteins - genetics Whole exome sequencing
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!