The mechanistic landscape of Lytic transglycosylase as targets for antibacterial therapy

Lytic transglycosylases (Ltgs) are glycan strand cleaving enzymes whose role is poorly understood in the genesis of the bacterial envelope. They play multiple roles in all stages of a bacterial life cycle, by creating holes in the peptidoglycan that is necessary for cell division and separation. Her...

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Veröffentlicht in:	Current opinion in structural biology 2022-12, Vol.77, p.102480-102480, Article 102480
Hauptverfasser:	Martinez-Bond, Elizabeth A., Soriano, Berliza M., Williams, Allison H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Bacteria Bacterial Proteins beta-Lactams - pharmacology Cell Wall Glycosyltransferases Peptidoglycan
Online-Zugang:	Volltext
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