The role of p53‐MDM2 signaling in missed abortion and possible pathogenesis

Background Missed abortion is one of the common obstetrical and gynecological complications, angiogenesis is the most important factor in fetal and placental development. However, the definite etiology and pathogenesis are not fully understood. Methods The mRNA levels of p53, MDM2, VEGF, and HIF‐lα...

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Veröffentlicht in:	The journal of obstetrics and gynaecology research 2022-11, Vol.48 (11), p.2686-2696
Hauptverfasser:	Liu, Ting, Yan, Min, Liu, Fen, Ma, Yuyan, Fang, Yan
Format:	Artikel
Sprache:	eng
Schlagworte:	Abortion Angiogenesis Cell cycle Correlation analysis Etiology Fetuses Flow cytometry G1 phase Hypoxia Immunohistochemistry MDM2 MDM2 protein missed abortion p53 p53 Protein Pathogenesis Polymerase chain reaction Pregnancy S phase Vascular endothelial growth factor
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