Blast phase of chronic myeloid leukemia with concurrent BCR::ABL1 and SET::NUP214: A report of two cases

Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm defined by the presence of t(9;22)(q34;q11.2)/BCR::ABL1. Additional chromosomal abnormalities play an important role in the progression to CML. However, the additional fusion gene was rarely reported such as CBFB::MYH11. In this report,...

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Veröffentlicht in:	Molecular carcinogenesis 2023-02, Vol.62 (2), p.117-121
Hauptverfasser:	Chen, Yan, Wang, Qian, Cen, Jiannong, Xu, Chao, Tao, Ting‐ting, Xie, Jundan, Shen, Wenhong, Gong, Yanlei, Pan, Jinlan, Yao, Li
Format:	Artikel
Sprache:	eng
Schlagworte:	BCR-ABL protein BCR::ABL1 Blast Crisis - genetics blast phase Chromosome aberrations Chronic myeloid leukemia Diagnosis Disease resistance Fusion protein Fusion Proteins, bcr-abl - genetics Fusion Proteins, bcr-abl - metabolism Genetic transformation Humans Leukemia, Myelogenous, Chronic, BCR-ABL Positive - diagnosis Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics Myeloid leukemia Nuclear Pore Complex Proteins Protein Kinase Inhibitors - pharmacology Protein Kinase Inhibitors - therapeutic use Protein-tyrosine kinase Retrospective Studies SET::NUP214
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