Concise enantioselective synthesis of non-proteinogenic α-aminoacids via an organocatalytic Mannich-type reaction

A bifunctional tertiary amine-squaramide-catalyzed enantioselective Mannich-type addition of available allomaltol to N -protected aldimines was developed. The resulted adducts were readily transformed into non-proteinogenic α-amino acids and their derivatives were not easily accessible by other meth...

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2022-11, Vol.58 (92), p.12827-12830
Hauptverfasser:	Kovalevsky, Ruslan A., Kucherenko, Alexander S., Zlotin, Sergei G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adducts Amino acids Enantiomers Esterification Optical properties Optical rotation
Online-Zugang:	Volltext
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