Comparison of transcriptomic profiles in edge to center of plaque reveals chronological molecular events in psoriatic plaque formation

Peripheral edge (PE) of plaques contains inflammatory molecules and has potential to initiate plaque formation, while the center (CE) of plaques has regression trends. To elucidate the chronological molecular events by comparing the gene profiles in PE skin to those in CE skin. Biopsied PE, CE, and...

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Veröffentlicht in:	Journal of dermatological science 2022-10, Vol.108 (1), p.30-38
Hauptverfasser:	Boonpethkaew, Suphagan, Meephansan, Jitlada, Jumlongpim, Onjira, Charoensuksira, Sasin, Tangtanatakul, Pattarin, Wongpiyabovorn, Jongkonnee, Komine, Mayumi
Format:	Artikel
Sprache:	eng
Schlagworte:	Chronic skin disease Cytokines Genes Humans Inflammation Inflammation - metabolism Interleukins - metabolism Pathogenesis Psoriasis - pathology RNA-sequencing Skin - pathology Skin Abnormalities Transcriptome
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