From Cold to Hot: Changing Perceptions and Future Opportunities for Quantitative Systems Pharmacology Modeling in Cancer Immunotherapy

Immuno‐oncology (IO) is a fast‐expanding field due to recent success using IO therapies in treating cancer. As IO therapies do not directly kill tumor cells but rather act upon the patients’ own immune cells either systemically or in the tumor microenvironment, new and innovative approaches are requ...

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Veröffentlicht in:	Clinical pharmacology and therapeutics 2023-05, Vol.113 (5), p.963-972
Hauptverfasser:	Lemaire, Vincent, Bassen, David, Reed, Mike, Song, Roy, Khalili, Samira, Lien, Yi Ting (Kayla), Huang, Lu, Singh, Aman P., Stamatelos, Spyros, Bottino, Dean, Hua, Fei
Format:	Artikel
Sprache:	eng
Schlagworte:	Drug Development Humans Immunotherapy Medical Oncology Models, Biological Neoplasms - drug therapy Network Pharmacology Pharmacology Tumor Microenvironment
Online-Zugang:	Volltext
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