Optimization design of sialic acid derivatives enhances the performance of liposomes for modulating immunosuppressive tumor microenvironments

Sialic acid derivatives (SA-derivatives) provide a nanomedicine platform for tumor-targeted delivery and treatment, and allow modulation of immunosuppressive tumor microenvironments with excellent therapeutic effects. Further, the multi-reactive groups of sialic acid (SA) contribute to the diversity...

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Veröffentlicht in:	Life sciences (1973) 2022-12, Vol.310, p.121081-121081, Article 121081
Hauptverfasser:	Sui, Dezhi, Liang, Kaifan, Gui, Yangxu, Du, Zhouchunxiao, Xin, Dongzhe, Yu, Guojing, Zhai, Wantong, Liu, Xinrong, Song, Yanzhi, Deng, Yihui
Format:	Artikel
Sprache:	eng
Schlagworte:	CD8+ T cells Doxorubicin Liposomes Sialic acid-cholesterol conjugate Sialic acid-derivatives Tumor associated macrophages
Online-Zugang:	Volltext
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