Low-dose 5-fluorouracil ameliorates Th2 responses through the induction of apoptotic cell death of lung monocyte-derived dendritic cells in asthma

5-Fluorouracil (5-FU) is an analog of pyrimidine and has been shown to display antitumor and immunomodulatory effects. However, the impacts of 5-FU in regulating asthma, an inflammatory disease associated with T helper cell 2 (Th2) responses, remain unclear. Here, we determine the modulatory effects...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2022-12, Vol.156, p.113875-113875, Article 113875
Hauptverfasser:	Deng, Nishan, Zuo, Xiaoshu, lin, Qibin, Wang, Tong, Li, Yun, Zhong, Jieying, Ni, Haiyang, Chen, Qianhui, Ding, Xuhong, Yu, Hongying, Nie, Hanxiang
Format:	Artikel
Sprache:	eng
Schlagworte:	5-fluorouracil Apoptotic cell death Asthma Monocyte-derived dendritic cells Th2 cell responses
Online-Zugang:	Volltext
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