In Vivo Nitroreductase Imaging via Fluorescence and Chemical Shift Dependent 19 F NMR

Nitroreductase (NTR) is an important biomarker widely used to evaluate the degree of tumor hypoxia. Although a few optical methods have been reported for detecting nitroreductase at low concentration ranges, an effective strategy for nitroreductase monitoring in vivo without limits to the imaging de...

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Veröffentlicht in:	Angewandte Chemie International Edition 2022-12, Vol.61 (50), p.e202213495-e202213495
Hauptverfasser:	Chen, Shizhen, Xiao, Long, Li, Yu, Qiu, Maosong, Yuan, Yaping, Zhou, Rui, Li, Conggang, Zhang, Lei, Jiang, Zhong-Xing, Liu, Maili, Zhou, Xin
Format:	Artikel
Sprache:	eng
Schlagworte:	Fluorescent Dyes - chemistry Humans Magnetic Resonance Imaging Microscopy, Fluorescence - methods Neoplasms - diagnostic imaging Nitrogen Dioxide Nitroreductases - chemistry Optical Imaging - methods Tumor Microenvironment
Online-Zugang:	Volltext
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