18β-glycyrrhetinic acid protects neuronal cells from ferroptosis through inhibiting labile iron accumulation and preventing coenzyme Q10 reduction

Ferroptosis is a new form of iron-dependent cell death. A growing body of evidence suggests that abnormal ferroptosis is involved in developing neurodegenerative diseases. 18β-glycyrrhetinic acid (GA) is a major bioactive component of licorice with multiple biological activities including neuroprote...

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Veröffentlicht in:	Biochemical and biophysical research communications 2022-12, Vol.635, p.57-64
Hauptverfasser:	Ma, Xuan, Chen, Hui, Cao, Lixing, Zhao, Shuang, Zhao, Chong, Yin, Shutao, Fan, Lihong, Hu, Hongbo
Format:	Artikel
Sprache:	eng
Schlagworte:	18β-glycyrrhetinic acid Animals Coenzyme Q10 Ferroptosis Iron Licorice Mice Neuroprotection Neuroprotective Agents - pharmacology
Online-Zugang:	Volltext
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