The Effect of BTK Inhibitor Ibrutinib on Leishmania infantum Infection In Vitro

Purpose Leishmaniasis is a neglected infectious disease affecting millions of people worldwide. Visceral leishmaniasis (VL), caused by Leishmania infantum and Leishmania donovani, is one of the main clinical forms of the disease and fatal if not treated promptly and properly. Despite being available...

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Veröffentlicht in:	Acta parasitologica 2022-12, Vol.67 (4), p.1732-1739
Hauptverfasser:	Mert, Ufuk, Müftüoğlu, Can, Erdem, Sevgi, Sadıqova, Aygül, Toz, Seray, Ozbel, Yusuf, Caner, Ayse
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Systematics/Taxonomy/Biogeography Biomedical and Life Sciences Biomedicine Bruton's tyrosine kinase Cell viability Chemotherapy Ecology Enzyme inhibitors Health services Infectious diseases Intracellular signalling Kinases Leishmania infantum Lymphocytes B Macrophages Malignancy Medical Microbiology Microbiology Original Paper Parasites Parasitic diseases Parasitology Protein-tyrosine kinase Side effects Targeted cancer therapy Toxicity Tyrosine Vector-borne diseases Visceral leishmaniasis
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