Urine metabolomics reveals biomarkers and the underlying pathogenesis of diabetic kidney disease

Purpose Diabetic kidney disease (DKD) is the most common complication of type 2 diabetes mellitus (T2DM), and its pathogenesis is not yet fully understood and lacks noninvasive and effective diagnostic biomarkers. In this study, we performed urine metabolomics to identify biomarkers for DKD and to c...

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Veröffentlicht in:	International urology and nephrology 2023-04, Vol.55 (4), p.1001-1013
Hauptverfasser:	Luo, Maolin, Zhang, Zeyu, Lu, Yongping, Feng, Weifeng, Wu, Hongwei, Fan, Lijing, Guan, Baozhang, Dai, Yong, Tang, Donge, Dong, Xiangnan, Yun, Chen, Hocher, Berthold, Liu, Haiping, Li, Qiang, Yin, Lianghong
Format:	Artikel
Sprache:	eng
Schlagworte:	Albuminuria - complications Amino acids Bioinformatics Biomarkers Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 Diabetic Nephropathies - diagnosis Diabetic Nephropathies - etiology Diabetic Nephropathies - metabolism Diabetic nephropathy Ferroptosis Humans Kidney diseases Liquid chromatography Mass spectroscopy Medicine Medicine & Public Health Metabolism Metabolites Metabolomics Metabolomics - methods Nephrology Nephrology - Original Paper Pathogenesis Signal transduction Tyramine Urine Urology
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